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Association between hyponatremia, mortality and hospitalization in patients with acute decompensated Heart Failure

Asociación entre hiponatremia, mortalidad y estancia hospitalaria en pacientes con falla cardíaca descompensada

dc.creatorDiaztagle-Fernández, Juan José
dc.creatorChaves-Saltiago, Walter Gabriel
dc.creatorSprockel-Díaz, John Jaime
dc.creatorAcevedo-Velasco, Andrés David
dc.creatorRodríguez-Benítez, Fredy Hernán
dc.creatorBenavides-Solarte, Mario Fernando
dc.creatorRodríguez-Niño, María Angélica
dc.creatorVillamizar-Quintero, Álvaro José
dc.creatorBotero-Jaramillo, Giovanna
dc.creatorPlazas-Vargas, Francy Liliana
dc.date2019-11-29
dc.date.accessioned2022-03-03T21:02:36Z
dc.date.available2022-03-03T21:02:36Z
dc.identifierhttps://revistas.unab.edu.co/index.php/medunab/article/view/3497
dc.identifier10.29375/01237047.3497
dc.identifier.urihttp://test.repositoriodigital.com:8080/handle/123456789/16463
dc.descriptionIntroduction. Hyponatremia is the most common electrolyte disorder in patients with chronic heart failure affecting up to 28% of patients at admission. It has been shown to be an independent predictor of mortality, extended length of hospital stay and rehospitalization. The objective is to evaluate the presence of hyponatremia in patients with decompensated heart failure and describe its relationship with length of hospital stay and mortality. Methodology. A prospective cohort study in patients hospitalized at internal medicine service at a high level of complexity hospital in Bogotá, Colombia diagnosed with decompensated heart failure  between April  2011 and March 2012. Sodium was measured on admission, 72 hours and at the seventh day of hospitalization. We evaluated the association between hyponatremia at hospital admission, mortality at 30 days and length of hospital stay. Results. 162 patients were included with an average age of 72 years, 52.5% male. Forty-one (25.3%) had hyponatremia at admission. Among the patients with normal sodium at admission, 6 had hyponatremia at 72 hours and 2 at the seventh day. In-hospital mortality in the total population was 9.2%, in the hyponatremia group 12.2%, and 8.2% in those who did not have it (p = 0.45). The average length of hospital stay was higher in patients with hyponatremia, 6.6 vs 8.4 days (p = 0.12). Discussion. The incidence of hyponatremia at admission in this group of patients was similar to that reported in the literature. Conclusions. The results showed a trend towards higher mortality and hospital stay in patients with hyponatremia, even though it was not statistically significant.en-US
dc.descriptionIntroducción. La hiponatremia es la alteración electrolítica más frecuente en pacientes con falla cardíaca crónica, que afecta hasta el 28% de pacientes en el ingreso hospilatario. Se ha demostrado que es un predictor independiente de mortalidad, estancia prolongada y rehospitalización. El objetivo es describir la frecuencia de hiponatremia en pacientes con falla cardíaca descompensada y su relación con la estancia hospitalaria y mortalidad. Metodología. Cohorte prospectiva en pacientes hospitalizados por el servicio de Medicina Interna en un hospital de cuarto nivel de Bogotá, Colombia, con diagnóstico de falla cardíaca descompensada entre abril de 2011 y marzo de 2012. Se midió el sodio al ingreso, a las 72 horas y al día séptimo de hospitalización. Se evaluó la relación de la hiponatremia al ingreso con la estancia hospitalaria y la mortalidad intrahospitalaria a 30 días. Resultados. Se incluyeron 162 pacientes, con promedio de edad de 72 años, 52.5% hombres. Cuarenta y uno (25.3%) presentaron hiponatremia al ingreso. Entre los pacientes que presentaron sodio normal al ingreso, 6 presentaron hiponatremia a las 72 horas y 2 a los 7 días. La mortalidad intrahospitalaria en la población total fue 9.2%, en el grupo de hiponatremia 12.2%, y 8.2% en los que no la tuvieron (p= 0.45). El promedio de estancia hospitalaria fue superior en los pacientes con hiponatremia, 6.6 vs. 8.4 días (p= 0.12). Discusión. La incidencia de hiponatremia al ingreso en este grupo de pacientes fue semejante a la reportada en la literatura. Conclusiones. Existe una tendencia hacia una mayor mortalidad y estancia hospitalaria en pacientes con hiponatremia, aun cuando no fue estadísticamente significativa.es-ES
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dc.languagespa
dc.languageeng
dc.publisherUNABes-ES
dc.relationhttps://revistas.unab.edu.co/index.php/medunab/article/view/3497/3146
dc.relationhttps://revistas.unab.edu.co/index.php/medunab/article/view/3497/3147
dc.relationhttps://revistas.unab.edu.co/index.php/medunab/article/view/3497/3171
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dc.sourceMedUNAB; Vol. 22 No. 3 (2019): december 2019 - march 2020: Cancer pain, Heart failure, Obesity; 294-303en-US
dc.sourceMedUNAB; Vol. 22 Núm. 3 (2019): diciembre 2019 - marzo 2020: Dolor oncológico, Falla cardíaca, Obesidad; 294-303es-ES
dc.source2382-4603
dc.source0123-7047
dc.subjectHeart failureen-US
dc.subjectHyponatremiaen-US
dc.subjectPrognosisen-US
dc.subjectMortalityen-US
dc.subjectHospitalizationen-US
dc.subjectInsuficiencia cardíacaes-ES
dc.subjectHiponatremiaes-ES
dc.subjectPronósticoes-ES
dc.subjectMortalidades-ES
dc.subjectHospitalizaciónes-ES
dc.titleAssociation between hyponatremia, mortality and hospitalization in patients with acute decompensated Heart Failureen-US
dc.titleAsociación entre hiponatremia, mortalidad y estancia hospitalaria en pacientes con falla cardíaca descompensadaes-ES
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion


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