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Direct Oral Anticoagulants: General principles and reversion of bleeding at emergency service. A literature review.

Reversión de anticoagulantes orales directos: una perspectiva desde Urgencias

dc.creatorZuluaga-Gómez, Mateo
dc.creatorZuluaga-Arbeláez, Nicolás
dc.creatorBerrouet-Mejía, Marie Claire
dc.creatorEstrada-Atehortúa, Andrés Felipe
dc.date2020-11-26
dc.date.accessioned2022-03-03T21:03:13Z
dc.date.available2022-03-03T21:03:13Z
dc.identifierhttps://revistas.unab.edu.co/index.php/medunab/article/view/3841
dc.identifier10.29375/01237047.3841
dc.identifier.urihttp://test.repositoriodigital.com:8080/handle/123456789/16502
dc.descriptionIntroduction. Bleeding in the context of anticoagulation is one of the risks faced by some patients during certain treatments, and is potentially deadly. It is important to be aware of the pharmacokinetics of these molecules in order to predict their behavior. Clinical judgment is also required in all cases of bleeding, because management will depend on its severity. The purpose of this review is to present an approach to an anticoagulated patient with bleeding in the emergency ward. Topics Discussed. Pharmacokinetics and pharmacodynamics, generalities, major and non- major bleeding, reversal options and treatment. Conclusion. If direct oral anticoagulants (DOACS) are present, it is necessary to assess the severity of bleeding and the degree of anticoagulation, because the management treatment depends on whether bleeding is major or minor.en-US
dc.descriptionIntroducción. El sangrado en contexto de anticoagulación es uno de los riesgos que tienen ciertos pacientes durante determinados tratamientos, y es potencialmente mortal. Es importante conocer la farmacocinética de estas moléculas para predecir cuál será su comportamiento. Además se requiere juicio clínico en todos los casos de sangrado para determinar el manejo de acuerdo a la severidad. El objetivo de esta revisión es presentar un enfoque del paciente anticoagulado con sangrado en el servicio de urgencias. Temas tratados. Farmacocinética y farmacodinámica, generalidades, sangrado mayor y no mayor, opciones de reversión y tratamiento. Conclusión. En presencia de anticoagulantes orales directos (DOACS) se debe evaluar la gravedad del sangrado y el grado de anticoagulación, pues las estrategias de manejo se orientan dependiendo de si se trata de un sangrado mayor o menor.es-ES
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dc.languagespa
dc.publisherUNABes-ES
dc.relationhttps://revistas.unab.edu.co/index.php/medunab/article/view/3841/3358
dc.relationhttps://revistas.unab.edu.co/index.php/medunab/article/view/3841/3377
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dc.rightsDerechos de autor 2020 MedUNABes-ES
dc.rightshttps://creativecommons.org/licenses/by-nc/4.0es-ES
dc.sourceMedUNAB; Vol. 23 No. 3 (2020): december 2020 - march 2021: Depression, Urinary Tract Infections, Occupational Burnout; 483-490en-US
dc.sourceMedUNAB; Vol. 23 Núm. 3 (2020): diciembre 2020 - marzo 2021: Depresión, Infecciones Urinarias, Agotamiento Profesional; 483-490es-ES
dc.source2382-4603
dc.source0123-7047
dc.subjectDirect anticoagulantsen-US
dc.subjectbleedingen-US
dc.subjectidarucizumaben-US
dc.subjectandexaneten-US
dc.subjectBlood-Derivative Drugsen-US
dc.subjectAnticoagulantes directoses-ES
dc.subjectsangradoes-ES
dc.subjectidarucizumabes-ES
dc.subjectandexanetes-ES
dc.subjectMedicamentos Hemoderivadoses-ES
dc.titleDirect Oral Anticoagulants: General principles and reversion of bleeding at emergency service. A literature review.en-US
dc.titleReversión de anticoagulantes orales directos: una perspectiva desde Urgenciases-ES
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion


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