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Histological Findings in Very Low Risk Prostate Cancer Patients Managed with Radical Prostatectomy

dc.creatorTrujillo Ordoñez, Carlos Gustavo
dc.creatorRamos Hernández, Anamaria
dc.creatorRobledo Cárdenas, Daniela
dc.creatorMariño Álvarez, Ángela Marcela
dc.creatorCataño Cataño, Juan Guillermo
dc.creatorCaicedo Cárdenas, Juan Ignacio
dc.creatorEscobar Monroy, Rebeca
dc.creatorPlata Salazar, Mauricio
dc.date2020-04-15T18:21:05Z
dc.date2020-04-15T18:21:05Z
dc.date2017-09-27
dc.date.accessioned2025-10-30T14:06:12Z
dc.date.available2025-10-30T14:06:12Z
dc.identifierhttp://revistas.javeriana.edu.co/index.php/vnimedica/article/view/20114
dc.identifier10.11144/Javeriana.umed58-3.risk
dc.identifier2011-0839
dc.identifier0041-9095
dc.identifierhttp://hdl.handle.net/10554/30087
dc.identifier.urihttp://test.repositoriodigital.com:8080/handle/123456789/193986
dc.descriptionAbstractObjectives: To describe the histological findings in patients with prostate cancer (PCa) clinically classified as very low risk who underwent treatment with radical prostatectomy (RP). Material and methods: A retrospective observational study was conducted. Clinical records of patients who underwent RP between 2007-2015 who met Epstein criteria for very low risk disease were reviewed. Histological diagnosis was described and analyzed to determine if such criteria predicted very low risk. Results: A total of 609 records were reviewed; 83 (13.6%) met Epstein’s criteria. Mean age was 59 (SD±7) years and median PSA at diagnosis was 5.4 ng/dl (IQR 4.3 – 6.8). Pathology showed a median tumor volume of 4% (IQR 1 – 10%). Gleason score was 3+3 in 55 (66.3%) cases, but 28 (33.7%) were reclassified to a greater score. Two (2.4%) patients were reclassified as pT3a, 80 (96.4%) as pT2 and 1 (1.2%) was found to be pT0. In those subjected to pelvic lymphadenectomy (42.2%) no positive lymph nodes were found. Conclusions: Up to one-third of the patients clinically classified with very low risk PCa had a greater Gleason score. Only 3% had locally advanced tumors, which is comparable to previous studies. Epstein’s criteria seem to be adequate in predicting organ-confined disease. 
dc.formatPDF
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dc.formatapplication/pdf
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dc.languageeng
dc.languagespa
dc.publisherPontificia Universidad Javeriana
dc.relationhttp://revistas.javeriana.edu.co/index.php/vnimedica/article/view/20114/16841
dc.relationhttp://revistas.javeriana.edu.co/index.php/vnimedica/article/view/20114/15965
dc.relationhttp://revistas.javeriana.edu.co/index.php/vnimedica/article/view/20114/20611
dc.relationUniversitas Medica; Vol 58 No 3 (2017)
dc.relationUniversitas Medica; Vol. 58 Núm. 3 (2017)
dc.rightsDerechos de autor 2017 Carlos Gustavo Trujillo Ordoñez, Anamaria Ramos Hernández, Daniela Robledo Cárdenas, Ángela Marcela Mariño Álvarez, Juan Guillermo Cataño Cataño, Juan Ignacio Caicedo Cárdenas, Rebeca Escobar Monroy, Mauricio Plata Salazar
dc.rightsAtribución-NoComercial-SinDerivadas 4.0 Internacional
dc.rightshttp://creativecommons.org/licenses/by/4.0
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttp://purl.org/coar/access_right/c_abf2
dc.titleHistological Findings in Very Low Risk Prostate Cancer Patients Managed with Radical Prostatectomy
dc.typehttp://purl.org/coar/version/c_970fb48d4fbd8a85
dc.typeArtículo de revista
dc.typehttp://purl.org/coar/resource_type/c_6501
dc.typeinfo:eu-repo/semantics/article
dc.typeArtículo revisado por pares


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