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Stauffer syndrome, clinical implications and knowledge gaps, does size matter? case report

dc.contributorPontificia Universidad Javeriana. Facultad de Medicina. Departamento de Cirugía y Especialidades. Urología
dc.contributorPontificia Universidad Javeriana. Facultad de Medicina. Hospital Universitario San Ignacio
dc.contributorCataño Cataño, Juan Guillermo
dc.contributorVillaquirán-Torres, Claudio
dc.contributorPatino, German
dc.creatorChavarriaga, Julian
dc.creatorFakih, Nayib
dc.creatorCataño Cataño, Juan Guillermo
dc.creatorVillaquiran Torres, Catalina
dc.creatorRodriguez, Santiago
dc.creatorPatino, German
dc.date2022-05-31T17:11:29Z
dc.date2022-05-31T17:11:29Z
dc.date2020-07-20
dc.date.accessioned2025-10-30T14:07:31Z
dc.date.available2025-10-30T14:07:31Z
dc.identifierhttps://bmcurol.biomedcentral.com/articles/10.1186/s12894-020-00671-w
dc.identifier1471-2490
dc.identifierhttp://hdl.handle.net/10554/60038
dc.identifierhttps://doi.org/10.1186/s12894-020-00671-w
dc.identifierinstname:Pontificia Universidad Javeriana
dc.identifierreponame:Repositorio Institucional - Pontificia Universidad Javeriana
dc.identifierrepourl:https://repository.javeriana.edu.co
dc.identifier.urihttp://test.repositoriodigital.com:8080/handle/123456789/194376
dc.descriptionBackground: Stauffer Syndrome (SS) is a paraneoplastic disorder associated with renal cell carcinoma (RCC). First described by Herbert Maurice Stauffer in 1961, it is characterized by hepatic dysfunction in the absence of metastasis, and elevated alkaline phosphatase, aminotransferases and prolonged prothrombin time. Initial reports did not include jaundice as an inclusion criterion. We aim to report the rare SS jaundice variant in a patient with a small renal mass and review the literature to determine if the size of the renal mass could influence the development of the SS. Case presentation: The aim of this article is to present the case of a 53-year-old male with Stauffer syndrome jaundice variant secondary to a 2.5 cm renal mass, treated with laparoscopic radical nephrectomy with complete resolution of the syndrome. Conclusions: This syndrome is yet to be fully understood, and as far as the evidence shows, size does not matter. This entity should always be in mind when encountered with a patient with liver dysfunction and jaundice with a suspicion or confirmed diagnosis of a renal mass. To date, and to our knowledge, there have been eleven reported cases of paraneoplastic cholestatic jaundice syndrome including the current case. Six cases presented in patients with small renal mases (< 4 cm), curiously there were not a laterality tendency.
dc.descriptionQ3
dc.descriptionQ2
dc.descriptionPacientes con Síndrome de Stauffer
dc.descriptionhttps://orcid.org/0000-0003-0363-5485
dc.descriptionhttps://orcid.org/0000-0002-2226-8871
dc.descriptionhttps://orcid.org/0000-0001-8202-9744
dc.descriptionhttps://orcid.org/0000-0002-3743-6268
dc.descriptionhttps://orcid.org/0000-0002-7495-5139
dc.descriptionRevista Internacional - Indexada
dc.descriptionA2
dc.descriptionNo
dc.formatPDF
dc.formatapplication/pdf
dc.formatapplication/pdf
dc.languageeng
dc.relation1
dc.relation5
dc.relationBMC Urology
dc.relation20
dc.rightsAtribución-NoComercial 4.0 Internacional
dc.rightshttp://creativecommons.org/licenses/by-nc/4.0/
dc.rightshttp://purl.org/coar/access_right/c_abf2
dc.subjectCarcinomas
dc.subjectRenal Cell
dc.subjectParaneoplastic Syndrome
dc.subjectLiver Dysfunctions
dc.subjectJaundice
dc.subjectCholestatic
dc.subjectCase Report
dc.titleStauffer syndrome, clinical implications and knowledge gaps, does size matter? case report
dc.typehttp://purl.org/coar/version/c_ab4af688f83e57aa
dc.typeReporte de caso
dc.typehttp://purl.org/coar/resource_type/c_6501


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