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Factors associated with in-hospital mortality in octogenarians managed by geriatric service in a referral hospital in Colombia
Factors associated with in-hospital mortality in octogenarians managed by geriatric service in a referral hospital in Colombia
| dc.contributor | Pontificia Universidad Javeriana. Facultad de Medicina. Instituto de Envejecimiento | |
| dc.contributor | Chavarro-Carvajal, Diego Andrés | |
| dc.contributor | Muñoz, Oscar Mauricio | |
| dc.contributor | Cortes Bahamon, Carlos Mario | |
| dc.contributor | Rodríguez Ángel, Jenny | |
| dc.contributor | Ballesteros Tapias, Jennifer Katherine | |
| dc.creator | Cortes Bahamon, Carlos Mario | |
| dc.creator | Rodríguez Ángel, Jenny | |
| dc.creator | Ballesteros Tapias, Jennifer Katherine | |
| dc.creator | Chavarro-Carvajal, Diego Andrés | |
| dc.creator | Muñoz, Oscar Mauricio | |
| dc.date | 2025-02-19T21:07:23Z | |
| dc.date | 2025-02-19T21:07:23Z | |
| dc.date | 2025-01-13 | |
| dc.date.accessioned | 2025-10-30T14:07:57Z | |
| dc.date.available | 2025-10-30T14:07:57Z | |
| dc.identifier | https://journals.sagepub.com/home/SMO | |
| dc.identifier | 2050-3121 | |
| dc.identifier | http://hdl.handle.net/10554/69603 | |
| dc.identifier | https://doi.org/10.1177/205031212513173 | |
| dc.identifier | instname:Pontificia Universidad Javeriana | |
| dc.identifier | reponame:Repositorio Institucional - Pontificia Universidad Javeriana | |
| dc.identifier | repourl:https://repository.javeriana.edu.co | |
| dc.identifier.uri | http://test.repositoriodigital.com:8080/handle/123456789/194502 | |
| dc.description | Introducción: La transición demográfica ha aumentado significativamente el número de hospitalizaciones en pacientes octogenarios. Estudios anteriores han documentado la importancia de las variables clínicas, funcionales y cognitivas para el riesgo de mortalidad hospitalaria. pero aún no se ha descrito su frecuencia e importancia en las poblaciones latinoamericanas. Es importante porque Colombia Tenemos múltiples razas étnicas, con diferentes tipos de longevidad, y tenemos una historia de violencia social que afecta nuestra vida. expectativa. El objetivo de este estudio es definir qué factores de riesgo se asocian con la mortalidad hospitalaria en octogenarios, y su frecuencia y cuantificar el peso de cada uno de estos factores en los resultados. Metodología: Presentamos un estudio de cohorte retrospectivo observacional analítico en pacientes adultos mayores de 80 años. hospitalizado y seguido por el servicio de geriatría del Hospital Universitario San Ignacio (Bogotá, Colombia). la asociación entre la mortalidad hospitalaria y múltiples variables clínicas, funcionales y cognitivas se evaluó mediante análisis univariados y análisis de regresión logística multivariado. Resultados: Se analizaron un total de 1.235 hospitalizaciones (edad 85,5 ± 4,4 años, 58,62% mujeres). Se documentó desnutrición en el 22,4%, dependencia para actividades básicas (Barthel 95) en el 75,9% y detección positiva de fragilidad (FRAIL 3) en el 55,3%. La mortalidad fue del 5,67%. Los factores asociados de forma independiente con la mortalidad fueron los antecedentes de cáncer (Odds ratio (OR): 2,31; 95% Intervalo de confianza (IC): 1,34–3,98, p < 0,003), delirio (OR: 2,48; IC 95%: 1,44–4,28, p < 0,001), desnutrición (OR: 2,50; IC 95%: 1,46–4,28; p = 0,001), fragilidad (OR: 2,25; IC 95%: 1,13-4,45, p = 0,019), taquipnea al ingreso (OR: 1,09; IC 95%: 1,03-1,14, p = 0,002) y elevación de creatinina (OR: 2,47; IC 95%: 1,47-4,15, p = 0,001). Conclusión: Los factores fácilmente identificables al ingreso hospitalario y susceptibles de intervención podrían predecir un mayor riesgo de mortalidad en pacientes octogenarios, como la presencia de desnutrición, fragilidad y delirio. Estos hallazgos facilitan la estimación del riesgo de mortalidad y servir como punto de partida para investigar el beneficio potencial de las intervenciones tempranas en esta población. | |
| dc.description | Q2 | |
| dc.description | Q2 | |
| dc.description | Introduction: The demographic transition has significantly increased the number of hospitalizations in octogenarian patients. Previous studies have documented the importance of clinical, functional, and cognitive variables for in-hospital mortality risk, but their frequency and importance in Latin American populations is yet to be described. It is important because Colombia has multiple ethnic races, with different types of longevity, and we have a history of social violence that affects our life expectancy. The aim of this study is to define which risk factors are associated with in-hospital mortality in octogenarians, and how frequent they are and quantify the weight of each of these factors in the outcomes. Methodology: We present an analytical observational retrospective cohort study in adult patients over 80 years of age hospitalized and followed by the geriatrics service at Hospital Universitario San Ignacio (Bogotá, Colombia). The association between in-hospital mortality and multiple clinical, functional, and cognitive variables was evaluated by means of univariate and multivariate logistic regression analysis. Results: A total of 1235 hospitalizations were analyzed (age 85.5 ± 4.4 years, 58.62% women). Malnutrition was documented in 22.4%, dependency for basic activities (Barthel ⩽ 95) in 75.9%, and positive screening for frailty (FRAIL ⩾ 3) in 55.3%. Mortality was 5.67%. Factors independently associated with mortality were history of cancer (Odds ratio (OR): 2.31; 95% Confidence interval (CI): 1.34–3.98, p < 0.003), delirium (OR: 2.48; 95% CI: 1.44–4.28, p < 0.001), malnutrition (OR: 2.50; 95% CI: 1.46–4.28; p = 0.001), frailty (OR: 2.25; 95% CI: 1.13–4.45, p = 0.019), tachypnea on admission (OR: 1.09; 95% CI: 1.03–1.14, p = 0.002), and creatinine elevation (OR: 2.47; 95% CI: 1.47–4.15, p = 0.001). Conclusion: Factors easily identifiable at hospital admission and amenable to intervention could predict an increased risk of mortality in octogenarian patients, such as the presence of malnutrition, frailty, and delirium. These findings facilitate the estimation of mortality risk and serve as a starting point to investigate the potential benefit of early interventions in this population. | |
| dc.description | https://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0001337521 | |
| dc.description | https://scholar.google.com/citations?user=ns-9aAgAAAAJ&hl=es&oi=ao | |
| dc.description | https://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0001337521 | |
| dc.description | N/A | |
| dc.description | Si | |
| dc.format | ||
| dc.format | application/pdf | |
| dc.format | application/pdf | |
| dc.language | eng | |
| dc.relation | 1 | |
| dc.relation | 7 | |
| dc.relation | SAGE Open Medicine | |
| dc.relation | 13 | |
| dc.rights | Atribución-NoComercial 4.0 Internacional | |
| dc.rights | http://creativecommons.org/licenses/by-nc/4.0/ | |
| dc.rights | http://purl.org/coar/access_right/c_abf2 | |
| dc.subject | Delirio | |
| dc.subject | adultos mayores | |
| dc.subject | fragilidad | |
| dc.subject | fragilidad, mortalidad | |
| dc.subject | mortalidad hospitalaria | |
| dc.subject | desnutrición | |
| dc.subject | Delirium | |
| dc.subject | older adults | |
| dc.subject | frailty | |
| dc.subject | hospital mortality | |
| dc.subject | hospital mortality | |
| dc.subject | malnutrition | |
| dc.title | Factors associated with in-hospital mortality in octogenarians managed by geriatric service in a referral hospital in Colombia | |
| dc.title | Factors associated with in-hospital mortality in octogenarians managed by geriatric service in a referral hospital in Colombia | |
| dc.type | http://purl.org/coar/version/c_ab4af688f83e57aa | |
| dc.type | Artículo de revista | |
| dc.type | http://purl.org/coar/resource_type/c_2df8fbb1 |
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