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Desarrollo de linfomas y leucemias mediado por disbiosis intestinal derivada de la administración prolongada de antibióticos. Revisión narrativa de la literatura

dc.creatorLaverde-Güiza, María José
dc.creatorBeltrán-Sierra, Andrea Catalina
dc.creatorCortés-Forero, Paula Valentina
dc.creatorRodríguez-Martin, Sandra Liliana
dc.date2025-04-30
dc.date2025-12-19T21:12:11Z
dc.date2025-12-19T21:12:11Z
dc.date.accessioned2026-03-25T19:35:03Z
dc.date.available2026-03-25T19:35:03Z
dc.identifierhttps://revistas.umng.edu.co/index.php/smed/article/view/7897
dc.identifier10.18359/19099061.7897
dc.identifierhttps://hdl.handle.net/10654/48590
dc.identifier.urihttp://test.repositoriodigital.com:8080/handle/123456789/202256
dc.descriptionEste artículo de revisión tiene como objetivo establecer la conexión entre los cambios de la microbiota gastrointestinal inducidos por el consumo prolongado de antibióticos y su impacto en el proceso de hematopoyesis, y cómo esto conduce al desarrollo de neoplasias de línea blanca como leucemias y linfomas. Para lograr este objetivo, se realizó una búsqueda bibliográfica en diversas bases de datos electrónicas como PubMed, Scopus, ClinicalKey y AccessMedicine, centrándose en estudios de la última década, de 2014 a 2024. Mediante el empleo de los descriptores en salud MeSH (“gastrointestinal microbiome”, “mielopoiesis”, “dysbiosis”, “anti-bacterial agents”, “leukemia”) y DeCS (“microbioma gastrointestinal”, “mielopoyesis”, “disbiosis”, “antibacterianos”, “leucemia”), se seleccionaron estudios clínicos aleatorizados controlados y revisiones de la literatura. Los resultados obtenidos revelan que la disbiosis intestinal, provocada por la administración descontrolada y prolongada de antibióticos, interfiere con procesos inmunológicos críticos, que inducen a alteraciones en la hematopoyesis y predisponen al desarrollo de malignidades hematológicas. Se concluye que existe una relación significativa entre la perturbación de la microbiota gastrointestinal y la incidencia de trastornos oncólogo-hematológicos, subrayando la necesidad de moderar el uso de agentes antibacterianos para mitigar estos efectos adversos
dc.formatapplication/pdf
dc.languagespa
dc.publisherUniversidad Militar Nueva Granada
dc.relationhttps://revistas.umng.edu.co/index.php/smed/article/view/7897/6373
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dc.rightsDerechos de autor 2025 Semilleros med
dc.sourceSemilleros med.; Vol. 18 Núm. 1 (2024): Semilleros med; 61-74
dc.source1909-9061
dc.subjectmicrobioma gastrointestinal
dc.subjectmielopoyesis
dc.subjectdisbiosis
dc.subjectantibacterianos
dc.subjectleucemia
dc.titleDesarrollo de linfomas y leucemias mediado por disbiosis intestinal derivada de la administración prolongada de antibióticos. Revisión narrativa de la literatura
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion


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