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Treatment with gonadotropin-releasing hormone analogs (GnRHa) in childhood and adolescence [Tratamiento con análogos de la hormona liberadora de gonadotrofinas (aGnRH) en niñas, niños y adolescents]

dc.creatorBoulgourdjian, Elisabeth M.
dc.creatorAlonso, Guillermo
dc.creatorArcari, Andrea
dc.creatorBengolea, Sonia V.
dc.creatorCostanzo, Mariana
dc.creatorD'Amato, Silvia
dc.creatorKeselman, Ana
dc.creatorMartin, Silvia
dc.creatorPipman, Viviana R.
dc.creatorAzrak, María S.
dc.date2022
dc.date.accessioned2022-11-01T19:35:04Z
dc.date.available2022-11-01T19:35:04Z
dc.identifierhttp://pa.bibdigital.ucc.edu.ar/3226/1/A_Martin_Boulgourdjian_Alonso.pdf
dc.identifier.urihttp://test.repositoriodigital.com:8080/handle/123456789/43766
dc.descriptionFor several decades, gonadotropin releasing hormone analogs (GnRHa) are the medical treatment selected for central precocious puberty (CPP) in girls and boys. They generate an inhibition of the hypothalamus-pituitary-gonadal axis decreasing LH, FSH, estradiol and testosterone secretion and, in this way, they produce a regression of secondary sexual characters under treatment. In the last years, these analogs are also used in trans adolescents, in adolescents and young adults with oncological diseases, in some very particular situations in children with short stature and in patients with neurodevelopmental disorders. In Argentina the most commonly used formulations are triptorelin and leuprolide acetate depot forms. These analogs have proven both their efficacy and their safety. The aim of this paper is to review and update about the use of GnRHa in children and adolescents.
dc.descriptionFil: Boulgourdjian, Elisabeth M. Hospital Italiano de Buenos Aires; Argentina
dc.descriptionFil: Alonso, Guillermo. Hospital Italiano de Buenos Aires; Argentina
dc.descriptionFil: Arcari, Andrea. Hospital de Niños Dr. Ricardo Gutiérrez; Argentina
dc.descriptionFil: Bengolea, Sonia V. Hospital General de Agudos Dr. Juan A. Fernández; Argentina
dc.descriptionFil: Costanzo, Mariana. Hospital de Pediatría S.A.M.I.C. Prof. Dr. Juan P. Garrahan; Argentina
dc.descriptionFil: D'Amato, Silvia. Hospital Nacional Posadas; Argentina
dc.descriptionFil: Keselman, Ana. Hospital de Niños Dr. Ricardo Gutiérrez; Argentina
dc.descriptionFil: Martin, Silvia. Universidad Católica de Córdoba. Clínica Universitaria Reina Fabiola; Argentina
dc.descriptionFil: Pipman, Viviana R. Hospital General de Agudos Dr. E. Tornú; Argentina
dc.descriptionFil: Azrak, María S. Hospital General de Agudos Dr. E. Tornú; Argentina
dc.formatapplication/pdf
dc.languagespa
dc.publisherSociedad Argentina de Pediatria
dc.relationhttp://pa.bibdigital.ucc.edu.ar/3226/
dc.relationhttps://www.sap.org.ar/docs/publicaciones/archivosarg/2022/v120n1a24s.pdf
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.5546/aap.2022.S9
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.sourceBoulgourdjian, Elisabeth M., Alonso, Guillermo, Arcari, Andrea, Bengolea, Sonia V., Costanzo, Mariana, D'Amato, Silvia, Keselman, Ana, Martin, Silvia, Pipman, Viviana R. and Azrak, María S. (2022) Treatment with gonadotropin-releasing hormone analogs (GnRHa) in childhood and adolescence [Tratamiento con análogos de la hormona liberadora de gonadotrofinas (aGnRH) en niñas, niños y adolescents]. Archivos Argentinos de Pediatria. ISSN 0325-0075
dc.subjectR Medicina (General)
dc.titleTreatment with gonadotropin-releasing hormone analogs (GnRHa) in childhood and adolescence [Tratamiento con análogos de la hormona liberadora de gonadotrofinas (aGnRH) en niñas, niños y adolescents]
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:ar-repo/semantics/artículo


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